咪唑并[1,2-a]吡啶-8-甲酸

咪唑并[1,2-a]吡啶-8-甲酸 - Names and Identifiers

Name	imidazo[1,2-A]pyridine-8-Carboxylic acid
Synonyms	Imidazo[1,2-a]pyridine-8-... Imidazo[1,2-a]pyridine-8-carboxylicaci 8-imidazo[1,2-a]pyridinecarboxylic acid IMidazo[1,2-a]pyridin-8-carboxylic acid imidazo[1,2-A]pyridine-8-Carboxylic acid IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID Imidazo[1,2-A]pyridine-8-carboxylic acid H-imidazo[1,2-a]pyridine-8-carboxylic acid H-iMidazo[1,2-a]pyridine-8-carbo×ylic acid
CAS	133427-08-4
InChI	InChI=1/C8H6N2O2/c11-8(12)6-2-1-4-10-5-3-9-7(6)10/h1-5H,(H,11,12)

咪唑并[1,2-a]吡啶-8-甲酸 - Physico-chemical Properties

Molecular Formula	C8H6N2O2
Molar Mass	162.15
Density	1.41
pKa	-0.61±0.41(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.676

咪唑并[1,2-a]吡啶-8-甲酸 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R43 - May cause sensitization by skin contact
Safety Description	36/37 - Wear suitable protective clothing and gloves.

咪唑并[1,2-a]吡啶-8-甲酸 - Introduction

Imidazole (1,2-are) pyridine-8-carboxylic acid is an organic compound with the chemical formula C11H9N3O2. The following is a detailed description of the properties, uses, preparation and safety information of imidazole (1,2-and) pyridine-8-carboxylic acid:

Nature:
Imidazole (1,2-and) pyridine-8-carboxylic acid is a solid with a melting point of about 200-201 degrees Celsius. It is stable under acidic conditions and can be hydrolyzed in alkaline solutions. It is soluble in organic solvents such as ethanol, dimethyl sulfoxide and methylene chloride. It is weakly acidic and can react with bases to form the corresponding salts.

Use:
Imidazole (1,2-and) pyridine-8-carboxylic acid has a wide range of applications in organic synthesis. It is a commonly used molecular template, which can be used to prepare molecular recognition agents, resolution dyes, resins and coordination polymers. In addition, it can also be used as pharmaceutical intermediates, coatings and dye synthesis.

Preparation Method:
There are various methods for preparing imidazole (1,2-and) pyridine-8-carboxylic acid. A common method is to obtain an intermediate by reacting 2-aminopyridine with pyrrolidone, and then performing an acylation reaction to obtain the target product.

Safety Information:
Imidazole (1,2-and) pyridine-8-carboxylic acid does not cause significant toxicity to humans under normal operating conditions. However, as an organic compound, proper laboratory safety practices should be followed for the use and handling of any chemical substance. When handling the compound, avoid contact with skin, eyes and mucous membranes, and ensure that the operation is carried out in a well-ventilated area.

Last Update：2024-04-09 20:45:29